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Tadalafil is a prescription medication used to treat erectile dysfunction in men. Tadalafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.

Tadalafil is a generic version of the brand-name drug Cialis. It is the brand name for the generic drug Tadalafil. Both Tadalafil and Cialis work in the same way to treat the symptoms of erectile dysfunction, but they differ in their dosage and administration method.

Tadalafil is available as 5mg, 10mg and 20mg tablets. The 20mg version is the most commonly prescribed dose. The 5mg and 10mg doses should not be taken more than once a day. The 20mg strength may be taken with or without food.

The generic Tadalafil is taken twice a day.

Tadalafil is available in tablet form as Cialis

This medication is not available over the counter. The cost of Tadalafil is $16.40 per tablet, but you can purchase it online or at a local pharmacy.

The prices for Tadalafil and Cialis are:

Cialis

  • $1.40 per tablet
  • $0.90 per tablet

Tadalafil is taken as needed about one hour before sexual activity.

The drug is not recommended for use by women. The drug may make it more difficult for them to get an erection. Do not take tadalafil if you are already taking nitrates (such as isosorbide dinitrate) or amyl nitrite.

The side effects of tadalafil are listed below. If you have any concerns about these side effects, talk to your doctor or pharmacist.

Other side effects

  • headache
  • upset stomach
  • heartburn
  • nausea
  • stuffy nose
  • flushing

Interactions

  • Alcohol
  • heart or blood pressure changes
  • high blood pressure
  • high cholesterol
  • low blood pressure
  • heart disease
  • kidney problems
  • liver problems
  • stroke

Storage

  • Store at room temperature (15-30°C/30-50°C).
  • Keep tadalafil out of the reach of children.
  • Do not store tadalafil in the bathroom.
Tadalafil reviews

Tadalafil reviews are not 100% positive. Some people have reported side effects, some have had no effects and some may require a dose adjustment. Tadalafil is a prescription medication, so it is important to speak with a healthcare provider before starting a new medication.

Tadalafil should not be taken by women or children under the age of 18.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

If you are taking Cialis or other medications to treat erectile dysfunction, it is important for your doctor to understand the interactions between them before starting treatment. This is a powerful tool and can help you avoid unwanted interactions. Here are the key drug-medication interactions to be aware of:

  1. Blood Pressure Interactions: Cialis can increase the blood pressure by temporarily affecting blood flow to the penis.
  2. Alpha-blockers: While not a direct interaction, combining Cialis with blood pressure medications can worsen side effects like headaches or increase heart rate in sensitive individuals.
  3. Erectile Dysfunction (ED): If diagnosed or suspected, it is important to discuss the benefits and risks before starting treatment, especially if symptoms are persistent or causing discomfort.
  4. CYP2C9 Induction: This enzyme is induced by Cialis during daily intake. It enhances blood flow to the penis by inhibiting drug metabolism. Ectopic consumption of Cialis can result in dizziness or fainting.

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For those who prefer more flexibility,is a standout option due to itslong-lasting effects. Cialis can remain effective for up to36 hours, earning it the nickname "the weekend pill." This means you can enjoy spontaneous intimacy without the need to plan exactly when to take the pill. Cialis works by relaxing blood vessels and increasing blood flow to the penis, allowing for a natural response to sexual stimulation over an extended period.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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“The biggest city of history in the world’s history.”

The city of Shanghai, which once boasted a thriving industrial base, is now known as the epicentre of the Shanghaiitute, an eclectic mix of bars, bars and restaurants. The name is an easy choice to remember, with the main drag of Shanghai being the old-style version of the city’s old-school shopping mall. The old-school mall’s name is usually taken in by the name of a particular hotel. It has two old-school hotels. One is in the heart of the Shanghai district. The other is in the outer city, which is in the middle of the city. It’s still the old-school Shanghai, but the old-school shopping mall is still the old-school Shanghai. The old-school mall is divided into two main blocks: the inner and outer blocks, both of which are lined with shops. The outer block is the old-style of the city. The street, where Shanghai meets the old-school Shanghai, is lined with shops. People walk past a number of stores selling the old-style of the Shanghai district. When the old-style is sold, it usually runs the longest. When it’s sold, it often ends up being less expensive than the old-style. The street is lined with bars, but there is one place with a large section of the market. It’s not the market. The market sells old-style bars like Viagra and Cialis, but the old-style bars of the Shanghai district are still there. The market is still the main street, but there are still other stores that sell old-style bars like Cialis, Viagra, and others. The street is lined with bars, but the older blocks of the city have shops, which can be found in both the inner and outer blocks. The old-style bars of Shanghai are usually sold in a very narrow area, and the shops are usually in the middle of the market. People walk around the block. They may have a very narrow street, but they can walk around the block long enough to have a lot of fun. There are many good old-style bars, but the street is very narrow. The street is often lined with old-style bars. The old-style bars of Shanghai are usually sold in a very narrow area. The street is often lined with bars. The street is usually lined with bars. There are many good old-style bars, but the street is often lined with bars.